Methyl paraben
Methyl hydroxybenzoate, also known as methyl paraben, relative average molecular mass of 152.15, is a white crystalline powder or colorless crystal, soluble in alcohol, ether and acetone, very slightly soluble in water. Methyl paraben is a kind of parabens, neutral, non-irritating, almost non-toxic good preservatives. The effect of mold and yeast is better, and the effect of bacteria is poor. At pH3 ~ 6, the antiseptic effect is the strongest and the nature is the most stable, and the above pH8 is gradually hydrolyzed, and the antibacterial effect is also weakened. Propyl paraben [0.02%(w/v)] is used in combination with methyl paraben [0.18%(w/v)] as a bacteriostatic agent in various injectable preparations.
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Methyl paraben
Detailed introduction
1. Product Description
Methyl hydroxybenzoate, also known as methyl paraben, relative average molecular mass of 152.15, is a white crystalline powder or colorless crystal, soluble in alcohol, ether and acetone, very slightly soluble in water. Methyl paraben is a kind of parabens, neutral, non-irritating, almost non-toxic good preservatives. The effect of mold and yeast is better, and the effect of bacteria is poor. At pH3 ~ 6, the antiseptic effect is the strongest and the nature is the most stable, and the above pH8 is gradually hydrolyzed, and the antibacterial effect is also weakened. Propyl paraben [0.02%(w/v)] is used in combination with methyl paraben [0.18%(w/v)] as a bacteriostatic agent in various injectable preparations.
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Product Name |
English Name |
CAS No. |
Item No. |
Packing specification |
Executive standard |
CDE Registration Number |
FDA Registration Number |
|
Methyl paraben |
Methylparaben |
99-76-3 |
F232-000500 |
500g/bottle |
CP/USP/EP/JP |
F20180000371(A) |
—— |
2. Product advantages
Special customization: multi-functional production workshop to meet the fine needs of different customer products.
Meet the needs of different regulatory market standards: CP/USP/EP/JP.
Lower impurity residue: strictly control the residue of impurities and pollutants.
Customized packaging: different sizes of packaging can be used according to customer needs.
Higher safety: strict control of microorganisms and endotoxins.
3. Product Application
Antimicrobial Preservatives:Hydroxyphenyl esters are widely used as antibacterial preservatives in pharmaceutical preparations and cosmetics. For example, the combination of methyl paraben and propyl paraben can be used as antibacterial preservatives for a variety of injections. Hydroxyphenyl esters are effective in a wide range of pH, can effectively inhibit gram-negative, positive bacteria, yeasts and molds, and have broad-spectrum antibacterial properties. The hydroxyphenyl esters may be used alone or in combination with each other or with other antibacterial agents.
4. Characteristic R & D service
1) National pharmacopoeia testing operation decomposition guidance
2) Customized specialty preparation services.
Key words:
paraben
combination
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