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Sucrose (low endotoxin)

Sucrose (sucrose) scientific name is β-D-six ring glucoside, the relative average molecular mass is 342.30, white crystalline powder or crystal. Sucrose is a non-reducing disaccharide composed of D-glucose and D-fructose linked to C1 and C2 through an oxygen bridge, which is easily hydrolysed into glucose and fructose in the presence of dilute acid and has reducibility.

Classification:

Pharmaceutical excipients for biologics

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Sucrose (low endotoxin)

Detailed introduction

1. Product Description

Sucrose (sucrose) scientific name is β-D-six ring glucoside, relative average molecular mass is 342.30, white crystalline powder or crystal. Sucrose is a non-reducing disaccharide composed of D-glucose and D-fructose linked to C1 and C2 through an oxygen bridge, which is easily hydrolysed into glucose and fructose in the presence of dilute acid and has reducibility. Sucrose is easily soluble in water, easy to hygroscopic and deliquescent under high humidity conditions, and is commonly used as a flavoring agent, adhesive, stabilizer and protective agent.

Product Name	English Name	CAS No.	Item No.	Packing specification	Executive standard	CDE Registration Number	FDA Registration Number
Sucrose (low endotoxin)	Sucrose (Low Endotoxin)	57-50-1	F244-000500	500g/bottle	CP/USP/EP/JP	F20209990217(A)	036348 (A)
Sucrose (low endotoxin)	Sucrose (Low Endotoxin)	57-50-1	F244-001000	1kg/bottle	CP/USP/EP/JP	F20209990217(A)	036348 (A)
Sucrose (low endotoxin)	Sucrose (Low Endotoxin)	57-50-1	F244-010000	10kg/barrel	CP/USP/EP/JP	F20209990217(A)	036348 (A)
Sucrose (low endotoxin)	Sucrose (Low Endotoxin)	57-50-1	F244-025000	25kg/barrel	CP/USP/EP/JP	F20209990217(A)	036348 (A)
Sucrose (low endotoxin)	Sucrose (Low Endotoxin)	57-50-1	F244-050000	50kg/barrel	CP/USP/EP/JP	F20209990217(A)	036348 (A)

2. Product advantages

Meet the requirements of different regulations and market standards: CP/USP/EP/JP;

Lower impurity residue: strictly control the product organic impurities and inorganic impurities residue, low color value (less than or equal to 45) to ensure lower organic impurities residue, low conductivity (less than or equal to 35 μS/cm) to ensure lower inorganic impurities residue;

More options: sucrose (low endotoxin) provides beet, sugar cane sources to meet different customer needs;

Customized packaging: different sizes of packaging can be used according to customer needs;

Higher safety: low endotoxin sugar strictly control microorganisms and endotoxin, using ultrafiltration, recrystallization and other processes to effectively remove bacterial endotoxin.

Product Name

English Name

endotoxin

Aerobic bacteria (TAMC)

Mold and Yeast (TYMC)

Escherichia coli

Sucrose (low endotoxin)

Sucrose (Low Endotoxin)

<0.5EU/g

<2.0EU/g

<100cfu/g

<10cfu/g

None

3. Product Application

Lyoprotectants for biological preparationsIn biological products, sucrose is mainly used as a protective agent, which has a good freeze-drying protective effect on proteins, and can also adjust the osmotic pressure. It is recognized as one of the most widely used and most effective freeze-drying protectants.

Biologics process excipientsVirus purification is an important part of biological products process, sucrose gradient density centrifugation is a common and effective means of virus purification.

Stabilizers of biologically active substances such as blood products, vaccines, cell tissues, etc.Sucrose is a non-reducing sugar that does not react with amino acids or proteins and can be used as a stabilizer.

Medium Supplement

biological products virus purification

osmotic pressure regulator

4. Characteristic R & D service

1. National Pharmacopoeia Detection Operation Decomposition Guidance

2. Customized specialty preparation services

Key words:

sucrose

low

endotoxin

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