Polysorbate 80
Polysorbate 80, also known as Tween 80, is chemically named polyoxyethylene (20) sorbitan monooleate. The relative average molecular weight is 1309.68. Sorbitan is used as the skeleton. The side chains are connected with three oxyethylene chains with hydrophilic characteristics and one aliphatic chain with lipophilic characteristics. Due to the hydrophilicity of ethylene oxide chain segments, polysorbate has a larger HLB value (15.0), it is a non-ionic hydrophilic surfactant with good performance and safety.
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Polysorbate 80
Detailed introduction
1. Product Description
Polysorbate 80, also known as Tween 80, is chemically named polyoxyethylene (20) sorbitan monooleate. The relative average molecular weight is 1309.68. Sorbitan is used as the skeleton. The side chains are connected with three oxyethylene chains with hydrophilic characteristics and one aliphatic chain with lipophilic characteristics. Due to the hydrophilicity of ethylene oxide chain segments, polysorbate has a larger HLB value (15.0), it is a non-ionic hydrophilic surfactant with good performance and safety.
|
Product Name |
English Name |
CAS No. |
Item No. |
Packing specification |
Executive standards |
CDE Registration Number |
FDA Registration Number |
|
Polysorbate 80 |
Polysorbate 80 |
9005-65-6 |
F104-025000 |
25kg/barrel |
CP/USP/EP/JP |
F20209990224(A) |
-- |
2. Product advantages
Lower impurity residues: strict control of product free fatty acid and peroxide residues, strict control of ethylene glycol, diethylene glycol, triethylene glycol impurity residues;
Higher safety: the use of plant-derived fatty acid raw materials, strict control of microorganisms and endotoxins, to meet the injection, eye, inhalation and other high-risk routes of administration needs;
Meet the needs of different regulatory market standards: CP/USP/EP/JP.
3. Product Application
Surfactant:Polysorbates (PS) are a family of amphiphilic, nonionic surfactants.
Solvents:It has strong hydrophilicity and chemical stability, can improve the solubility of the active ingredients of the poorly soluble active drug, and is widely used in oral, parenteral and topical preparations, and is used as a solubilizer for essential oils and oil-soluble vitamins.
Emulsifier:As a hydrophilic nonionic surfactant, it is widely used as an emulsifier for stable oil-in-water drug emulsions.
4. Characteristic R & D service
1. National Pharmacopoeia Detection Operation Decomposition Guidance
2. Customized specialty preparation services
Key words:
polysorbate
hydrophilic
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